New england medical journal - New England Journal of Medicine 2024; 390:346-356. DOI: 10.1056/NEJMra2301903. Article, Jan. 2024 in Affective Computing · Media Lab Research …

 
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N Engl J Med 2024;390:1030-1043. A 55-year-old man had an out-of-hospital cardiac arrest. An evaluation showed 2-mm ST-segment elevations in the inferior leads on ... Xu and X.-t. Wang. Perspective Mar 7, 2024. “OK, Boomer” — NOS Episode 2.5. Review Article Feb 29, 2024. Cardiac Rehabilitation — Challenges, Advances, and the Road Ahead. R. J. Thomas ...E.S. Spatz and Others. N Engl J Med 2024;390:346-356. This article reviews the use of digital wearable technologies for monitoring of three common cardiovascular conditions: hypertension, heart ...Patients and Treatment Table 1. Table 1. Demographic and Disease Characteristics of the Patients at Baseline. Between June 1, 2020, and December 22, 2021, a total of 557 patients were randomly ...The new england journal of medicine 1268 n engl j med 382;13 nejm.org March 26, 2020 ... of this new disease within China and through-out the rest of the world. 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Rachel Gotbaum: Welcome to “Intention to Treat” from the New England Journal of Medicine.I’m Rachel Gotbaum. Today, we have the second part of our special series on Dr. Anthony Fauci. Fauci ...The Plight of DEI Leaders — Heavy Expectations and Limited Protection. Aletha Maybank, M.D., M.P.H. As leaders of diversity, equity, and inclusion efforts within academic, …Timing of Complete Revascularization for Myocardial Infarction. 91-92. Esketamine Nasal Spray versus Quetiapine for Resistant Depression. 93-95. Gastrointestinal Angiodysplasia before and after ...C.H. Jamieson and I.L. Weissman. N Engl J Med 2023;389:1310-1319. Stem cells can renew themselves without differentiating. Aging, inflammation, and environmental exposures may drive phenotypic ...Mar 23, 2021 · Early Results of SARS-CoV-2 Vaccination. In the initial 31 days of the vaccination campaign, 59% of 23,234 UTSW employees received a first dose of either one of the mRNA vaccines and 30% received ... Perspective Aug 03, 2023 AI and Medical Education A. Cooper and A. Rodman N Engl J Med 2023; 389:385-387 Artificial intelligence could have broad implications for medical education. NEJM AI, a monthly journal from NEJM Group, publishes cutting-edge research and applications of artificial intelligence in clinical medicine.Article Types. When sending either new manuscripts or presubmission inquiries to the New England Journal of Medicine (NEJM), authors must classify their submissions as one of the article types ...Liver Transplantation. Liver transplantation, first performed in humans 60 years ago, has become the standard of care for patients with life-threatening liver disease (see Table S1 in the ... New England Journal of Medicine (NEJM) articles feature timely Article Metrics in an easy-to-use dashboard format at NEJM.org. Valuable for both NEJM authors and readers, Article Metrics are found ... Learn about the history and mission of the New England Journal of Medicine, the trusted source for essential findings in medicine. Watch videos of clinicians from different countries and …Dec 9, 2023 · Abdominal Ectopic Pregnancy. Guillaume Gorincour, M.D., Ph.D., and Malik Boukerrou, M.D., Ph.D. A 37-year-old woman presented with a 10-day history of abdominal pain. Physical examination was ... The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...Charlotte J. Haug, M.D., Ph.D., and Jeffrey M. Drazen, M.D. However, by the late 1970s, there was disappointment that the two main approaches to computing in medicine — rule-based systems and ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...Article Types. When sending either new manuscripts or presubmission inquiries to the New England Journal of Medicine (NEJM), authors must classify their submissions as one of the article types ... E.J. Rubin, L.R. Baden, T.H. Lee, and S. Morrissey. In this audio interview conducted on January 6, 2021, the editors are joined by cardiologist and primary care physician Thomas H. Lee to discuss ... C.H. Jamieson and I.L. Weissman. N Engl J Med 2023;389:1310-1319. Stem cells can renew themselves without differentiating. Aging, inflammation, and environmental exposures may drive phenotypic ...Thomas M. File, Jr., M.D., and Julio A. Ramirez, M.D. Community-acquired pneumonia is an acute infection of the pulmonary parenchyma in a patient who has acquired the infection in the community ...The New England Journal of Medicine. Case Challenge Nov 29, 2023 A Woman with Abnormal Movements and Confusion. A 68-year-old woman was admitted because of confusion and abnormal movements of the ...Case 26-2023: A 15-Year-Old Girl with Abdominal Pain and an Ovarian Mass. A.L. Zuckerman, A. Pourvaziri, D.H. Ebb, and B. Boyraz. A 15-year-old girl was evaluated for abdominal pain and ...Israel’s retaliatory offensive against Hamas in Gaza has killed almost 32,000 people, according to Palestinian health officials, displaced more than 85 per cent of the 2.3mn …The New England Journal of Medicine (NEJM) is the world’s leading medical journal and website. Published continuously for over 200 years, NEJM delivers high-quality, peer-reviewed research and ...A 48-year-old woman presented with fatigue and painful, swollen, whitened gums. Her white-cell count was 225,000 per cubic millimeter, and peripheral-blood flow cytometry and bone marrow biopsy ...A. Sacher and Others. N Engl J Med 2023;389:710-721. Among patients with cancers bearing the KRAS G12C mutation who received divarasib at a 400-mg dose, 56% with lung cancer, 36% with colorectal ... The New England Journal of Medicine (NEJM) is the world’s leading medical journal and website. Published continuously for over 200 years, NEJM delivers high-quality, peer-reviewed research and ... The New England Journal of Medicine. Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services. At the New England Journal of Medicine (NEJM), our mission is to publish the best research and information at the intersection of biomedical science and clinical practice. Our highly selective ...View more on Covid-19 >>. Explore a collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and …The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...Cavernous Malformations of the Central Nervous System. E.R. Smith. Cerebral cavernous malformations occur in 0.5% of the population; 85% are sporadic, and 15% are familial or …Ascariasis. Myoung Kuk Jang, M.D., and Ki Sung Lee, M.D. A 60-year-old woman presented to the outpatient clinic with vague abdominal discomfort that had developed over the previous several weeks ...Customer Service. +1-800-843-6356. +1-781-434-7888 (Outside U.S. & Canada) Contact Us. The New England Journal of Medicine (NEJM) employs a rigorous peer review and editing process to evaluate all ... N Engl J Med 2023;388:1692-1700. New recommendations and expanded genetic testing have reshaped the classification and treatment of neonatal seizures. This review emphasizes the importance of EEG ... High impact medical journal. Champion of better research, clinical practice & healthcare policy since 1840. For GPs, hospital doctors, educators, policymakers. ... Information gaps in England’s independent healthcare sector. ... A new BMJ series offers tangible actions clinicians can take to reduce the carbon footprint of healthcare.The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...S. Woloshin and Others. N Engl J Med 2023;389:1061-1064. The evidence for breast cancer screening of women in their 40s is insufficient to support a new public health imperative, given the ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...A.H. Diacon. N Engl J Med 2022;387:2380-2381. Tuberculosis is an important cause of death worldwide, and drug resistance is implicated in one third of the almost 2 million deaths from tuberculosis ...Catherine, Princess of Wales during a Portage Session for her 'Shaping Us' campaign on early childhood, taken September 27, 2023 in Sittingbourne, England. Paul … A personal subscription to NEJM empowers you to: Explore all NEJM.org content from 1990–present. Dive deep into the NEJM Archive (1812–1989) with 50 free online article views. Take advantage ... Food and Drug Administration, Silver Spring, MD. [email protected]. No potential conflict of interest relevant to this letter was reported. This letter was published on March 1, 2023, at ...Article Types. When sending either new manuscripts or presubmission inquiries to the New England Journal of Medicine (NEJM), authors must classify their submissions as one of the article types ...Dec 10, 2020 · A two-dose regimen of BNT162b2 (30 μg per dose, given 21 days apart) was found to be safe and 95% effective against Covid-19. The vaccine met both primary efficacy end points, with more than a 99 ... Jul 6, 2023 · From the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, and the Department of Medicine, Brigham and Women’s Hospital — both in Boston (M.K ... Thyroid Dermopathy in Graves’ Disease. D. Arjunan and S.K. Bhadada. N Engl J Med 2023;389:2376-2376. A 49-year-old woman with Graves’ disease presented with a 3-year history of skin changes on ...Weight loss of 10 to 15% (or more) is recommended in people with many complications of overweight and obesity (e.g., prediabetes, hypertension, and obstructive sleep apnea). 1,20,21,27 In the ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...N Engl J Med 2022;386:1742-1749. An 82-year-old woman presented to the emergency department with a 3-week history of severe low back pain, rigors, anorexia, difficulty ambulating, and a sensation ...A Breathtaking Discovery. J. Coraor Fried, J.J. Ross, Z.F. Weiss, B.D. Levy, and J. Loscalzo. A 76-year-old man presented with a 1-month history of worsening exertional dyspnea and fatigue. 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Audio Interview: Preparing for the Next Pandemic. E.J. Rubin and Others. In this audio interview conducted on April 24, 2023, the editors are joined by international infectious disease ... The New England Journal of Medicine (NEJM) is the world’s leading medical journal and website. Published continuously for over 200 years, NEJM delivers high-quality, peer-reviewed research and ... The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...More on AI in Medicine. Review Article Wearable Digital Health Technologies in Medicine Dec 28, 2023 Wearable Technology for Depressive Disorder S. Fedor and Others N Engl J Med 2023; 389:2457-2466Clinical Practice. Epistaxis. H. Seikaly. Initial management of epistaxis involves digital compression of the lower third of the nose for 15 to 20 minutes. Anterior bleeding not controlled with ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...Localized Prostate Cancer — Then and Now. O. Sartor. N Engl J Med 2023;388:1617-1618. Between 1999 and 2009 in the United Kingdom, 82,429 men between 50 and 69 years of age underwent prostate ...N Engl J Med 2017; 376:910-912. The lack of attention paid to the millions of children born to a parent with schizophrenia, bipolar disorder, or recurrent major depression is out of phase with the ...Localized Prostate Cancer — Then and Now. O. Sartor. N Engl J Med 2023;388:1617-1618. 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The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ... The New England journal of medicine. Other Title(s): NEJM New Eng J Med New Engl J Med N. England J. M. New Eng J Med New Engl J Med Continues: Boston medical and surgical journal ISSN 0096-6762 Publication Start Year: 1928 Frequency: Weekly Country of Publication: United States Publisher: Boston, Massachusetts Medical Society. Description: Digging into the Histology. R. Paknikar, L. Alpert, R.D. Cohen, B. Shogan, and D. Micic. A 33-year-old man with ulcerative colitis presented with bloody diarrhea, an 8-month history of worsening ...The New England Journal of Medicine (NEJM) is the world’s leading medical journal and website. Published continuously for over 200 years, NEJM delivers high-quality, peer-reviewed research and ...The multinational outbreak of mpox (formerly known as monkeypox) that began in 2022 resulted in more than 90,000 reported cases, over 150 deaths, and — importantly — a coordinated international response to a rapidly spreading infectious disease. 1 Because of decades of global preparedness efforts, vaccines and … The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. ... As the oldest continuously-published medical journal ... Rachel Gotbaum: Welcome to “Intention to Treat” from the New England Journal of Medicine.I’m Rachel Gotbaum. Today, we have the second part of our special series on Dr. Anthony Fauci. Fauci ...A.H. Diacon. N Engl J Med 2022;387:2380-2381. Tuberculosis is an important cause of death worldwide, and drug resistance is implicated in one third of the almost 2 million deaths from tuberculosis ...N Engl J Med 2023;389:2256-2266. Tebentafusp is a bispecific molecule that recognizes CD3 and gp100. In a trial in patients with uveal melanoma, median survival at 3 years of follow-up was 21.6 ...The New England Journal of Medicine. Case Challenge Nov 29, 2023 A Woman with Abnormal Movements and Confusion. A 68-year-old woman was admitted because of confusion and abnormal movements of the ...Case 26-2023: A 15-Year-Old Girl with Abdominal Pain and an Ovarian Mass. A.L. Zuckerman, A. Pourvaziri, D.H. Ebb, and B. Boyraz. A 15-year-old girl was evaluated for abdominal pain and ...N Engl J Med 2023;388:1692-1700. New recommendations and expanded genetic testing have reshaped the classification and treatment of neonatal seizures. This review emphasizes the importance of EEG ...Liver Transplantation. Liver transplantation, first performed in humans 60 years ago, has become the standard of care for patients with life-threatening liver disease (see Table S1 in the ...Medical Xpress provides news and updates on the latest research published in the New England Journal of Medicine, the oldest continuously published medical journal in the world. Browse …The New England Journal of Medicine. No, NEJM permits only one corresponding author per submission. This person is solely responsible for all correspondence with NEJM and will receive all emails ... Nov 30. NEJM Covid-19 Update. Listen to conversations with editors Eric Rubin and Lindsey Baden on the current coronavirus outbreak. HealthMap of the Coronavirus Outbreak. The HealthMap team from ... The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...Clinical Practice. Epistaxis. H. Seikaly. Initial management of epistaxis involves digital compression of the lower third of the nose for 15 to 20 minutes. Anterior bleeding not controlled with ...Food and Drug Administration, Silver Spring, MD. [email protected]. No potential conflict of interest relevant to this letter was reported. This letter was published on March 1, 2023, at ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...Charlotte J. Haug, M.D., Ph.D., and Jeffrey M. Drazen, M.D. However, by the late 1970s, there was disappointment that the two main approaches to computing in medicine — rule-based systems and ...Iron deficiency affects more than 2 billion people worldwide, 1 and iron-deficiency anemia remains the top cause of anemia, as confirmed by the analysis of a large number of reports on the burden ...NEJM Group offers a range of products, including the New England Journal of Medicine, to provide evidence-based and innovative solutions for health care practice and education. Learn …Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA. [email protected]. This article was published on December 16, 2023, at NEJM.org. December 21, 2023. N Engl J Med 2023; 389:e54. DOI ...Jan 11, 2024 · S. Woloshin and Others. N Engl J Med 2023;389:1061-1064. The evidence for breast cancer screening of women in their 40s is insufficient to support a new public health imperative, given the ... Jul 21, 2021 · Original Article from The New England Journal of Medicine — Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world.The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Review Article from The New England Journal of Medicine — Behçet’s Syndrome. ... The most trusted, influential source of new medical knowledge and clinical best practices in the world. The New England Journal of Medicine (NEJM) is recognized as the world’s leading medical journal and website. Published continuously for over 200 years, NEJM delivers high-quality,... The New England Journal of Medicine ... All individuals meeting International Committee of Medical Journal Editors (ICMJE) criteria for article authorship must be named as article authors ... E.S. Spatz and Others. N Engl J Med 2024;390:346-356. This article reviews the use of digital wearable technologies for monitoring of three common cardiovascular conditions: hypertension, heart ...This is about to change. In January 2022, the NEJM Group will begin publishing a new journal, NEJM Evidence. This monthly, peer-reviewed, online-only, general medical journal will publish original ...Timing of Complete Revascularization for Myocardial Infarction. 91-92. Esketamine Nasal Spray versus Quetiapine for Resistant Depression. 93-95. Gastrointestinal Angiodysplasia before and after ...H. Chemaitelly and Others N Engl J Med 2022; 387:1865-1876. The 10-μg dose of BNT162b2 led to modest, rapidly waning protection against Covid-19 in children 5 to 11 years old. The 30-μg dose in ...The Plight of DEI Leaders — Heavy Expectations and Limited Protection. Aletha Maybank, M.D., M.P.H. As leaders of diversity, equity, and inclusion efforts within academic, …Biomarker Changes during 20 Years Preceding Alzheimer’s Disease. J. Jia and Others. N Engl J Med 2024;390:712-722. In the 20 years before diagnosis, the time points at which biomarkers for ...An estimated 500,000 persons in the United States have chronic urticaria, with a prevalence of 0.23%. The disorder may occur at any age, but most affected patients are women, and patients of both ...Subacute thyroiditis begins with a prodrome of generalized myalgias, pharyngitis, low-grade fever, and fatigue. Patients then present with fever and severe neck pain, swelling, or both. Up to 50 ...New England Journal of Medicine 2024; 390:346-356. DOI: 10.1056/NEJMra2301903. Article, Jan. 2024 in Affective Computing · Media Lab Research …N Engl J Med 2023;389:2256-2266. Tebentafusp is a bispecific molecule that recognizes CD3 and gp100. In a trial in patients with uveal melanoma, median survival at 3 years of follow-up was 21.6 ...Thyroid Dermopathy in Graves’ Disease. D. Arjunan and S.K. Bhadada. N Engl J Med 2023;389:2376-2376. A 49-year-old woman with Graves’ disease presented with a 3-year history of skin changes on ...Ascariasis. Myoung Kuk Jang, M.D., and Ki Sung Lee, M.D. A 60-year-old woman presented to the outpatient clinic with vague abdominal discomfort that had developed over the previous several weeks ...This is about to change. In January 2022, the NEJM Group will begin publishing a new journal, NEJM Evidence. This monthly, peer-reviewed, online-only, general medical journal will publish original ...S. Woloshin and Others. N Engl J Med 2023;389:1061-1064. The evidence for breast cancer screening of women in their 40s is insufficient to support a new public health imperative, given the ...Aug 8, 2019 · Perspective from The New England Journal of Medicine — Abortion Rights in Peril — What Clinicians Need to Know ... The authorized source of trusted medical research and education for the ... The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...A.H. Diacon. N Engl J Med 2022;387:2380-2381. Tuberculosis is an important cause of death worldwide, and drug resistance is implicated in one third of the almost 2 million deaths from tuberculosis ...Abdominal Ectopic Pregnancy. Guillaume Gorincour, M.D., Ph.D., and Malik Boukerrou, M.D., Ph.D. A 37-year-old woman presented with a 10-day history of abdominal pain. Physical examination was ...The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...NEJM Perspective The Road Less Traveled. opens in new tab. This Double Take video from the New England Journal of Medicine presents the real-life case of a woman with progressive chest pain after a trip to Puerto Rico, where she spent time exploring local national parks and caves. Viewers are guided through the differential diagnosis of the …Rachel Gotbaum: Welcome to “Intention to Treat” from the New England Journal of Medicine.I’m Rachel Gotbaum. With the public health emergency for Covid now declared over and more than 1 ...The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of …The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world. Sign In Create Account Subscribe Sign In ...NEJM AI, a monthly journal from NEJM Group, publishes cutting-edge research and applications of artificial intelligence in clinical medicine. View issue. Save. ... The New England Journal of Medicine; NEJM Catalyst Innovations in Care Delivery; NEJM Evidence; NEJM AI; NEJM AI is a product of NEJM Group, a division of the …The New England Journal of Medicine The most trusted, influential source of new medical knowledge and clinical best practices in the world.Pulsed Field or Conventional Thermal Ablation for Paroxysmal Atrial Fibrillation. V.Y. Reddy and Others. In a randomized trial involving patients with paroxysmal atrial fibrillation, pulsed field ...Jul 6, 2023 · From the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, and the Department of Medicine, Brigham and Women’s Hospital — both in Boston (M.K ... Searchable medical archives of content since 1812 from the New England Journal of Medicine.Jan 11, 2024 · S. Woloshin and Others. N Engl J Med 2023;389:1061-1064. The evidence for breast cancer screening of women in their 40s is insufficient to support a new public health imperative, given the ... Increasing Exposure of Young Children to Illicit Fentanyl in the United States. N Engl J Med 2024;390:956-957. Reported exposures to illicit fentanyl in children younger than 6 years of age in the ...Monkeypox Monkeypox cases reported in the United Kingdom, Portugal, and Italy in May 2022 led the WHO to declare a global health emergency. The authors review the virology, epidemiology, clinical f...Address reprint requests to Dr. Peeters at the Department of Internal Medicine, Academic Center for Thyroid Diseases, Rm. D-430, Erasmus Medical Center, Postbus 2040, 3000 CA, Rotterdam, the ...Case 28-2021: A 37-Year-Old Woman with Covid-19 and Suicidal Ideation. C.S. North, E.M. Sorg, S. Youn, and J.T. Chu. A 37-year-old woman was admitted to the hospital because of suicidal ideation ... The New England Journal of Medicine. Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services. Magnesium Metabolism. Warren E. C. Wacker, M.D. *, and Bert L. Vallee, M.D. †. THE average adult human being has a whole-body content of 25 gm. of magnesium. Magnesium is the fourth of the ... Nov 30. NEJM Covid-19 Update. Listen to conversations with editors Eric Rubin and Lindsey Baden on the current coronavirus outbreak. HealthMap of the Coronavirus Outbreak. The HealthMap team from ... Rachel Gotbaum: Welcome to “Intention to Treat” from the New England Journal of Medicine.I’m Rachel Gotbaum. Today, we have the second part of our special series on Dr. Anthony Fauci. Fauci ...The Javelin Group LLC has requested to rezone the 3.7-acre property at 10405 E. Northwest Highway in Lake Highlands to allow for residential use, according to an application … The New England Journal of Medicine. Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services. The New England Journal of Medicine (NEJM) is the world’s leading medical journal and website. Published continuously for over 200 years, NEJM delivers high-quality, peer-reviewed research and ... E.J. Rubin, L.R. Baden, T.H. Lee, and S. Morrissey. 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